Jason R Abbott

4PUBLICATIONS
17CO-AUTHORS
Atomic and molecular physicsMolecular imaging (incl. electron microscopy and neutron diffraction)Molecular targetsGenome structure and regulation
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Publications (4)

|Jul 25, 2025
Discovery of BI-2493, a Pan-KRAS Inhibitor Showing In Vivo Efficacy.

Joachim Bröker, Alex G Waterson, Timothy R Hodges

|Jan 17, 2025
Discovery of Small Molecules that Bind to Son of Sevenless 2 (SOS2).

Krzysztof M Zak, Alex G Waterson, Leonhard Geist

|Oct 27, 2022
Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRASG12C Inhibitor.

Joachim Bröker, Alex G Waterson, Chris Smethurst

|Sep 12, 2018
Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS.

Timothy R Hodges, Jason R Abbott, Andrew J Little

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