Connor J Dwyer

7PUBLICATIONS
40CO-AUTHORS
TransgenesisApplied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)Molecular targetsHaematological tumoursCancer therapy (excl. chemotherapy and radiation therapy)
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Publications (7)

|Feb 13, 2026
WTX-124, a Conditionally Activated Wild-Type IL2, Maximizes the Therapeutic Index of IL2, Unlike "Non-Alpha" Muteins.

Christopher J Nirschl, Kulandayan K Subramanian, Heather R Brodkin

|Dec 05, 2025
T-cell Priming by High-Avidity Neoantigens in Lymph Nodes Augments Adoptive Immunotherapy.

Megen C Wittling, Amalia M Rivera-Reyes, Megan M Wyatt

|Oct 06, 2023
Progressively Enhancing Stemness of Adoptively Transferred T Cells with PI3Kδ Blockade Improves Metabolism and Antitumor Immunity.

Guillermo O Rangel Rivera, Connor J Dwyer, Hannah M Knochelmann

|Apr 19, 2023
mWTX-330, an IL-12 INDUKINE Molecule, Activates and Reshapes Tumor-Infiltrating CD8+ T and NK Cells to Generate Antitumor Immunity.

Christopher J Nirschl, Heather R Brodkin, Celesztina Domonkos

|Mar 22, 2023
The degree of T cell stemness differentially impacts the potency of adoptive cancer immunotherapy in a Lef-1 and Tcf-1 dependent manner.

Guillermo O Rangel Rivera, Connor J Dwyer, Hannah M Knochelmann

|May 09, 2020
Ex vivo blockade of PI3K gamma or delta signaling enhances the antitumor potency of adoptively transferred CD8+ T cells.

Connor J Dwyer, Dimitrios C Arhontoulis, Guillermo O Rangel Rivera

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