Leike Zhang

47PUBLICATIONS
116CO-AUTHORS
PharmacogenomicsMedical virologyMedical infection agents (incl. prions)Biomolecular modelling and designCheminformatics and quantitative structure-activity relationships
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Publications (47)

|Apr 27, 2026
SARS-CoV-2 3CLpro mutations T21I and E166A confer differential resistance to simnotrelvir, bofutrelvir, and ensitrelvir.

|Apr 21, 2026
The oral nucleoside analogue inhibitor VV251 effectively inhibits coinfection by respiratory syncytial virus and influenza A virus.

|Mar 26, 2026
Severe fever with thrombocytopenia syndrome virus infection of the male reproductive tract induces pathology and inflammation.

Yunfa Zhang, Lingyu Zhang, Huan Xu

|Mar 11, 2026
A clinical SARS-CoV-2 Mpro inhibitor blocks replication of multiple enteroviruses and confers oral in vivo protection in animal models.

Zhengyu Ye, Wenhao Dai, Shaolin Zhang

|Sep 16, 2025
An orally available 4'-fluorouridine prodrug inhibits SFTSV and LCMV infection.

Xiaoqin Jian, Tianwen Hu, Huan Xu

|May 22, 2025
Development of Orally Bioavailable Octahydroindole-Based Peptidomimetic Derivative as a Broad-Spectrum Inhibitor against HCoV-OC43 and SARS-CoV-2.

Shulei Hu, Yumin Zhang, Chenchen Wang

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Frequent Collaborators

11 joint publications

Yumin Zhang

10 joint publications

Gengfu Xiao

10 joint publications

Jingshan Shen

8 joint publications

Hong Liu