Melanie Alpaugh

7PUBLICATIONS
41CO-AUTHORS
Molecular targetsNeurology and neuromuscular diseasesCentral nervous system
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (7)

|Oct 22, 2026
Cas9 nickase-mediated contraction of CAG/CTG repeats is associated with phenotypic improvements in a Huntington's disease mouse model.

|Oct 13, 2026
Huntington's disease vasculopathy is barrier-type-selective and arteriolar-dominant with spatially-coupled astrogliosis and reversible by S1pr1 stimulation.

|Mar 06, 2025
Tau levels in platelets isolated from Huntington's disease patients serve as a biomarker of disease severity.

Melanie Alpaugh, Juan Lantero-Rodriguez, Andrea L Benedet

|Oct 25, 2024
Investigating the Interplay between Cardiovascular and Neurodegenerative Disease.

Jason Patrick Cousineau, Aimee Maria Dawe, Melanie Alpaugh

|Mar 09, 2022
A light-inducible protein clustering system for in vivo analysis of α-synuclein aggregation in Parkinson disease.

Morgan Bérard, Razan Sheta, Sarah Malvaut

|Oct 29, 2021
Prion-like properties of the mutant huntingtin protein in living organisms: the evidence and the relevance.

Melanie Alpaugh, Hélèna L Denis, Francesca Cicchetti

Pageof 2

Frequent Collaborators

5 joint publications

Francesca Cicchetti

1 joint publications

Hélèna L Denis

1 joint publications

Sarah Malvaut

1 joint publications

Maxime Teixeira