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Denise Rageot

3PUBLICATIONS

4CO-AUTHORS

Molecular targetsCheminformatics and quantitative structure-activity relationships

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Publications (3)

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|Aug 30, 2019

A Conformational Restriction Strategy for the Identification of a Highly Selective Pyrimido-pyrrolo-oxazine mTOR Inhibitor.

Chiara Borsari, Denise Rageot, Alix Dall'Asen

|Jun 28, 2019

(<i>S</i>)-4-(Difluoromethyl)-5-(4-(3-methylmorpholino)-6-morpholino-1,3,5-triazin-2-yl)pyridin-2-amine (PQR530), a Potent, Orally Bioavailable, and Brain-Penetrable Dual Inhibitor of Class I PI3K and mTOR Kinase.

Denise Rageot, Thomas Bohnacker, Erhan Keles

|Oct 26, 2018

Discovery and Preclinical Characterization of 5-[4,6-Bis({3-oxa-8-azabicyclo[3.2.1]octan-8-yl})-1,3,5-triazin-2-yl]-4-(difluoromethyl)pyridin-2-amine (PQR620), a Highly Potent and Selective mTORC1/2 Inhibitor for Cancer and Neurological Disorders.

Denise Rageot, Thomas Bohnacker, Anna Melone

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Frequent Collaborators

3 joint publications

Chiara Borsari

3 joint publications

Alexander M Sele

3 joint publications

Matthias P Wymann

2 joint publications

John E Burke

Frequent Collaborators

3 joint publications

Chiara Borsari

3 joint publications

Alexander M Sele

3 joint publications

Matthias P Wymann

2 joint publications

John E Burke

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