Erik De Clercq

69PUBLICATIONS
54CO-AUTHORS
Biologically active moleculesCheminformatics and quantitative structure-activity relationshipsBiomolecular modelling and designGene and molecular therapyMedical molecular engineering of nucleic acids and proteins
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Publications (69)

|Aug 27, 2026
On the Verge of the 3000th Publication: Reflections on Deceptions, Successes and Perspectives.

|Aug 13, 2026
Discovery of Potent 1,2,4-Triazole-Derived HIV Capsid Modulators with Dual-Stage Antiviral Activity via Targeting the Unexplored GTNQ Sub-Pocket Using a Multi-Site Binding Strategy.

|Mar 30, 2026
Rational Design of Broad-Spectrum Non-Nucleoside Reverse Transcriptase Inhibitors via Pharmacophore-Oriented Generative Artificial Intelligence.

Kun Zhang, Yuhan Lin, Ling Dong

|Jan 10, 2026
Pioneering Role of T.C. Merigan in the Treatment of Various Virus Infections.

Erik De Clercq

|Jan 09, 2026
Cyclization-Inspired Structural Optimization: Designing Potent Non-nucleoside Reverse Transcriptase Inhibitors with Enhanced Safety and Selectivity.

Yin-Xiang Zhang, Christophe Pannecouque, Erik De Clercq

|Oct 20, 2025
Structure- and Privileged Fragment-Based Iterative Optimization: Discovery of 2,4-Disubstituted-6-aminopyrimidines as Novel HIV-1 NNRTIs with Potent Activity against Drug-Resistant Strains and Favorable Safety Profiles.

Xiangkai Ji, Xiangyi Jiang, Heng Gao

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Frequent Collaborators

27 joint publications

Xinyong Liu

22 joint publications

Dongwei Kang

21 joint publications

Peng Zhan

14 joint publications

Fener Chen