Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Alexey Simakov

5PUBLICATIONS
16CO-AUTHORS
Molecular targetsBiomolecular modelling and designBiologically active moleculesGene and molecular therapy
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (5)

Sort by Publication Date:
|May 14, 2025
Nrf2 Activation and Antioxidant Properties of Chromone-Containing MTDLs for Alzheimer's Disease Treatment.

Alexey Simakov, Stecy Chhor, Lhassane Ismaili

|Aug 29, 2024
Discovery of New Highly Potent Histamine H<sub>3</sub> Receptor Antagonists, Calcium Channel Blockers, and Acetylcholinesterase Inhibitors.

Rim Malek, Kinga Sałat, Perle Totoson

|Jan 23, 2024
Design and Synthesis of Multi-Functional Ligands through Hantzsch Reaction: Targeting Ca<sup>2+</sup> Channels, Activating Nrf2 and Possessing Cathepsin S Inhibitory, and Antioxidant Properties.

Irene Pachón-Angona, Paul J Bernard, Alexey Simakov

|Jun 10, 2023
Exploring the Potential of Sulfonamide-Dihydropyridine Hybrids as Multitargeted Ligands for Alzheimer's Disease Treatment.

Imen Dakhlaoui, Paul J Bernard, Diana Pietrzak

|Jan 08, 2023
Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca<sup>2+</sup> Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation.

Rim Malek, Alexey Simakov, Audrey Davis

Pageof 1

Frequent Collaborators

5 joint publications

Lhassane Ismaili

4 joint publications

Helene Martin

3 joint publications

Krzysztof Jozwiak

1 joint publications

Audrey Davis

1 joint publications

Artur Wnorowski

1 joint publications

Patrick Dallemagne

1 joint publications

Christophe Rochais

1 joint publications

Paul J Bernard

1 joint publications

Maciej Maj

1 joint publications

Raphaël Cornu

Frequent Collaborators

5 joint publications

Lhassane Ismaili

4 joint publications

Helene Martin

3 joint publications

Krzysztof Jozwiak

1 joint publications

Audrey Davis

Top Related Videos

Protocol for the Differentiation of Human Induced Pluripotent Stem Cells into Mixed Cultures of Neurons and Glia for Neurotoxicity Testing
09:02

Protocol for the Differentiation of Human Induced Pluripotent Stem Cells into Mixed Cultures of Neurons and Glia for Neurotoxicity Testing

Published on : Jun 09, 2017

23.0K
A High-throughput Calcium-flux Assay to Study NMDA-receptors with Sensitivity to Glycine/D-serine and Glutamate
04:48

A High-throughput Calcium-flux Assay to Study NMDA-receptors with Sensitivity to Glycine/D-serine and Glutamate

Published on : Jul 10, 2018

9.2K
Synthesis of Triazole and Tetrazole-Functionalized Zr-Based Metal-Organic Frameworks Through Post-Synthetic Ligand Exchange
04:51

Synthesis of Triazole and Tetrazole-Functionalized Zr-Based Metal-Organic Frameworks Through Post-Synthetic Ligand Exchange

Published on : Jun 23, 2023

2.9K
See more related videos

Top Related Videos

Protocol for the Differentiation of Human Induced Pluripotent Stem Cells into Mixed Cultures of Neurons and Glia for Neurotoxicity Testing
09:02

Protocol for the Differentiation of Human Induced Pluripotent Stem Cells into Mixed Cultures of Neurons and Glia for Neurotoxicity Testing

Published on : Jun 09, 2017

23.0K
A High-throughput Calcium-flux Assay to Study NMDA-receptors with Sensitivity to Glycine/D-serine and Glutamate
04:48

A High-throughput Calcium-flux Assay to Study NMDA-receptors with Sensitivity to Glycine/D-serine and Glutamate

Published on : Jul 10, 2018

9.2K
Synthesis of Triazole and Tetrazole-Functionalized Zr-Based Metal-Organic Frameworks Through Post-Synthetic Ligand Exchange
04:51

Synthesis of Triazole and Tetrazole-Functionalized Zr-Based Metal-Organic Frameworks Through Post-Synthetic Ligand Exchange

Published on : Jun 23, 2023

2.9K
See more related videos