Mitsunori Shiroishi

6PUBLICATIONS
8CO-AUTHORS
Applied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)Cheminformatics and quantitative structure-activity relationshipsSupramolecular chemistryCharacterisation of biological macromoleculesMolecular targets
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (6)

|Feb 18, 2026
Enthalpy-Entropy Trade-Off Underlies Geometric Isomer Selectivity in Histamine H1 Receptor-Doxepin Interaction.

Hiroto Kaneko, Satoru Nagatoishi, Kouhei Tsumoto

|Dec 22, 2025
Activity-restoring mutations in the histamine H3 receptor increase constitutive activity and reduce structural stability.

Ami Nakajima, Hiroto Kaneko, Kosuke Oyama

|Jun 26, 2024
Binding characteristics of the doxepin E/Z-isomers to the histamine H1 receptor revealed by receptor-bound ligand analysis and molecular dynamics study.

Hiroto Kaneko, Ryunosuke Korenaga, Ryota Nakamura

|Sep 29, 2022
A methodology for creating mutants of G-protein coupled receptors stabilized in active state by combining statistical thermodynamics and evolutionary molecular engineering.

Taisei Yamamoto, Satoshi Yasuda, Rinshi S Kasai

Pageof 1