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James O'Connell

4PUBLICATIONS
9CO-AUTHORS
Applied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)Biomolecular modelling and designNanometrologyTumour immunology
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Journal

Publications (4)

Sort by Publication Date:
|Apr 07, 2023
Target occupancy biomarker assay development using a conformation-selective antibody against small-molecule-bound TNF.

Elizabeth S Hickford, James O'Connell, Alison Maloney

|Jan 26, 2021
A conformation-selective monoclonal antibody against a small molecule-stabilised signalling-deficient form of TNF.

Daniel J Lightwood, Rebecca J Munro, John Porter

|Jan 26, 2021
Structural insights into the disruption of TNF-TNFR1 signalling by small molecules stabilising a distorted TNF.

David McMillan, Carlos Martinez-Fleites, John Porter

|Dec 21, 2019
Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer.

James O'Connell, John Porter, Boris Kroeplien

Pageof 1

Frequent Collaborators

3 joint publications

John Porter

2 joint publications

David McMillan

2 joint publications

David Fox

2 joint publications

Elizabeth S Hickford

1 joint publications

Boris Kroeplien

1 joint publications

Daniel J Lightwood

1 joint publications

Geoffrey I Johnston

1 joint publications

Matthias Herrmann

1 joint publications

Tim Bourne

Frequent Collaborators

3 joint publications

John Porter

2 joint publications

David McMillan

2 joint publications

David Fox

2 joint publications

Elizabeth S Hickford

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