Xin-Yu Leng

4PUBLICATIONS
6CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsMedical bacteriologyChemical engineering designBiologically active molecules
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Publications (4)

|Oct 23, 2026
Discovery of Novel 2-(2-Benzimidazole)-Substituted Tetrahydrofur-ans as Potent and Selective NaV1.8 Inhibitors for the Treatment of Pain.

|Apr 04, 2026
Design, Synthesis, and Biological Evaluation of Pyrimido[4,5-b]indole Derivatives with Potent Activity against Multidrug-Resistant Gram-Negative Bacteria.

Yuzhi Liu, Xin-Yu Leng, Haiqiao Wang

|Mar 16, 2025
A practical synthesis of YZD-7082B, a novel orally bioavailable selective estrogen receptor degrader (SERD) for the treatment of ER+ breast cancer.

Yongqi He, Xin-Yu Leng, Runying Wang

|Nov 29, 2024
Discovery of Thiochroman Derivatives as Potent, Oral Selective Estrogen Receptor Degraders and Antagonists for the Treatment of Endocrine-Resistant Breast Cancer.

Dan Zhang, Zhengyu Lu, Yongqi He

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Frequent Collaborators

4 joint publications

Yushe Yang

2 joint publications

Dan Zhang

1 joint publications

Wenhao Hu

1 joint publications

Yongqi He