Lauren Ostermann

13PUBLICATIONS
49CO-AUTHORS
Molecular targetsGene and molecular therapyHaematological tumoursMedical infection agents (incl. prions)Metabolic medicine
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Publications (13)

|Aug 17, 2026
Dual MYC and GSPT1 Protein Degrader for MYC-Driven Hematologic Malignancies.

|Jul 13, 2026
The Novel Hypomethylating Agent NTX-301 Reprograms Epigenetic and Hippo Signaling Pathways and Exhibits Preclinical Activity in Venetoclax-Resistant and TP53-Mutant AML.

|Jul 03, 2025
Restoring p53 wild-type conformation in TP53-Y220C-mutant acute myeloid leukemia.

Bing Z Carter, Po Yee Mak, Edward Ayoub

|Dec 26, 2023
Mitochondrial regulation of GPX4 inhibition-mediated ferroptosis in acute myeloid leukemia.

Hiroki Akiyama, Ran Zhao, Lauren B Ostermann

|Nov 29, 2023
Enhanced TP53 reactivation disrupts MYC transcriptional program and overcomes venetoclax resistance in acute myeloid leukemias.

Yuki Nishida, Jo Ishizawa, Edward Ayoub

|Jun 23, 2023
Mdm2/p53 levels in bone marrow mesenchymal stromal cells are essential for maintaining the hematopoietic niche in response to DNA damage.

Rasoul Pourebrahim, Rafael Heinz Montoya, Zoe Alaniz

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Frequent Collaborators

13 joint publications

Michael Andreeff

8 joint publications

Bing Z Carter

7 joint publications

Steffen Boettcher

6 joint publications

Edward Ayoub