Barbara Czako

5PUBLICATIONS
22CO-AUTHORS
Epigenetics (incl. genome methylation and epigenomics)Biologically active moleculesCheminformatics and quantitative structure-activity relationshipsProteins and peptidesRegenerative medicine (incl. stem cells)
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Publications (5)

|Aug 29, 2023
A novel molecular class that recruits HDAC/MECP2 complexes to PU.1 motifs reduces neuroinflammation.

William T Ralvenius, Alison E Mungenast, Hannah Woolf

|Oct 13, 2021
Discovery of 6-[(3<i>S</i>,4<i>S</i>)-4-Amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-3-(2,3-dichlorophenyl)-2-methyl-3,4-dihydropyrimidin-4-one (IACS-15414), a Potent and Orally Bioavailable SHP2 Inhibitor.

Barbara Czako, Yuting Sun, Timothy McAfoos

|Jul 22, 2021
Discovery of IACS-9779 and IACS-70465 as Potent Inhibitors Targeting Indoleamine 2,3-Dioxygenase 1 (IDO1) Apoenzyme.

Matthew M Hamilton, Faika Mseeh, Timothy J McAfoos

|Oct 29, 2020
Discovery of IPN60090, a Clinical Stage Selective Glutaminase-1 (GLS-1) Inhibitor with Excellent Pharmacokinetic and Physicochemical Properties.

Michael J Soth, Kang Le, Maria Emilia Di Francesco

|Aug 14, 2020
Discovery of IACS-9439, a Potent, Exquisitely Selective, and Orally Bioavailable Inhibitor of CSF1R.

Barbara Czako, Joseph R Marszalek, Jason P Burke

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Frequent Collaborators

2 joint publications

Michael J Soth

1 joint publications

Matthew M Hamilton

1 joint publications

William T Ralvenius

1 joint publications

Alison E Mungenast