Jeffrey A Ruffolo

10PUBLICATIONS
24CO-AUTHORS
Powder and particle technologyDiscourse and pragmaticsSeparation technologiesBiofabricationApplied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)
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Publications (10)

|Feb 02, 2026
Customizing CRISPR-Cas PAM specificity with protein language models.

Stephen Nayfach, Aadyot Bhatnagar, Andrey Novichkov

|Sep 30, 2025
What does a language model know about proteins?

Jeffrey A Ruffolo

|Jul 31, 2025
Design of highly functional genome editors by modelling CRISPR-Cas sequences.

Jeffrey A Ruffolo, Stephen Nayfach, Joseph Gallagher

|Jan 20, 2025
Engineering of CRISPR-Cas PAM recognition using deep learning of vast evolutionary data.

Stephen Nayfach, Aadyot Bhatnagar, Andrey Novichkov

|Nov 04, 2024
AIntibody: an experimentally validated in silico antibody discovery design challenge.

M Frank Erasmus, Laura Spector, Fortunato Ferrara

|Jun 20, 2024
Toward enhancement of antibody thermostability and affinity by computational design in the absence of antigen.

Mark Hutchinson, Jeffrey A Ruffolo, Nantaporn Haskins

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Frequent Collaborators

3 joint publications

Ali Madani

3 joint publications

Jeffrey J Gray

2 joint publications

Alexander J Meeske

2 joint publications

Benjamin P Kleinstiver