Hong Shen

19PUBLICATIONS
28CO-AUTHORS
Molecular targetsCheminformatics and quantitative structure-activity relationshipsBiologically active moleculesMolecular medicineCardiology (incl. cardiovascular diseases)
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Publications (19)

|Nov 03, 2026
Rapid target engagement of KRAS G12C tricomplex inhibitor RO3903 overcomes resistance and drives durable tumor regression.

|Jul 22, 2026
Structure-Based Design of Potent TLR7/8/9 Triple Antagonists: Overcoming High Tissue Distribution and Reactive Metabolite Liabilities.

|Apr 20, 2026
Discovery of Naphthyridinone Derivatives as Selective PKMYT1/WEE1 Dual Inhibitors for Cancer Therapy.

|Jan 14, 2026
Discovery of Potent and Efficacious Influenza PB2 Inhibitors.

Jun Wu, Yongfu Liu, Dongbo Li

|Apr 08, 2025
Discovery of Naphthyridinone Derivatives as Selective and Potent PKMYT1 Inhibitors with Antitumor Efficacy.

Bo Chen, Xiaofeng Liu, Tong Mu

|Oct 06, 2023
Discovery of 4,5,6,7-Tetrahydropyrazolo[1.5-a]pyrizine Derivatives as Core Protein Allosteric Modulators (CpAMs) for the Inhibition of Hepatitis B Virus.

Buyu Kou, Zhisen Zhang, Xingchun Han

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Frequent Collaborators

9 joint publications

Wei Zhu

6 joint publications

Xuefei Tan

3 joint publications

Shuai Chen

3 joint publications

Jun Wu