Ernst Schönbrunn

22PUBLICATIONS
84CO-AUTHORS
Proteins and peptidesMedical devicesCheminformatics and quantitative structure-activity relationshipsMolecular targetsBiologically active molecules
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Publications (22)

|Jul 23, 2026
Late-stage functionalization with strain-release warheads enables tunable covalent inhibition.

|Apr 15, 2026
Structural Basis for BD1-Preferring 2,4-Disubstituted Pyrimidine BRDT Inhibitors.

|Jan 14, 2026
Structure-Activity and Structure-Degradation Relationship Studies of 2-Amino-6-(benzimidazol-2-ylmethyl)-N9-heteroarylpurines as Potent and Selective CDK12/13 Inhibitors and Cyclin K Degraders.

Thiyagamurthy Pandurangan, Solomon Tadesse Zeleke, Anna Iermolaieva

|May 16, 2025
PROTAC-Mediated Degradation of TAF1 Induces Apoptosis in AML Cells and Inhibits Tumor Growth In Vivo.

Lihong Chen, Zachary P Shultz, Marianna Sansone

|Oct 25, 2024
Discovery and design of molecular glue enhancers of CDK12-DDB1 interactions for targeted degradation of cyclin K.

Pompom Ghosh, Maximilian Schmitz, Thiyagamurthy Pandurangan

|Apr 25, 2024
Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition.

Noha A M Shendy, Melissa Bikowitz, Logan H Sigua

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Frequent Collaborators

8 joint publications

Gunda I Georg

6 joint publications

Luxin Sun

5 joint publications

William C K Pomerantz

4 joint publications

Andrii Monastyrskyi