John G Doench

96PUBLICATIONS
586CO-AUTHORS
Molecular targetsGravimetricsEpigenetics (incl. genome methylation and epigenomics)Medical molecular engineering of nucleic acids and proteinsTransgenesis
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Publications (96)

|Sep 02, 2026
Therapy-persistent leukemia is selectively vulnerable to SLC23A1 restoration via targeting KHSRP.

|Jul 22, 2026
Oncogenic Gα signaling requires AP-3-dependent recruitment to the endolysosomal compartment.

|Jul 16, 2026
A transcriptional biosensor reveals mechanisms of α-ketoglutarate signaling to chromatin.

|Jun 29, 2026
Discovery of Tcf7 regulators with clonally-resolved CRISPR screens identifies Trim28 as a mediator of CD8 T cell differentiation in tumors.

|May 08, 2026
CRISPR base editor screening identifies spectrum of MEN1 mutations impacting menin inhibitors in clinical trials.

|May 04, 2026
CD164 is an endolysomal host factor for entry of Clade A New World Arenaviruses.

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Frequent Collaborators

11 joint publications

David E Root

9 joint publications

Mudra Hegde

7 joint publications

Todd R Golub

7 joint publications

Martin W LaFleur