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Ruth Steele

6PUBLICATIONS
36CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsCellular nervous systemMedical molecular engineering of nucleic acids and proteinsInnate immunityBiologically active molecules
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Journal

Publications (6)

Sort by Publication Date:
|Nov 19, 2025
A Novel Small Molecule Allosteric Inhibitor of IL-17A from a DNA-Encoded Library.

Marcos E Milla, Jonathan M Blevitt, Steven D Goldberg

|Feb 17, 2025
Design, Synthesis, and Characterization of GluN2A Negative Allosteric Modulators Suitable for In Vivo Exploration.

François P Bischoff, Sven Van Brandt, Marcel Viellevoye

|Jun 21, 2024
Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in KMT2A- and NPM1-altered leukemias.

Min Chul Kwon, Jan Willem Thuring, Olivier Querolle

|Jan 04, 2024
Structural basis of the human NAIP/NLRC4 inflammasome assembly and pathogen sensing.

Rosalie E Matico, Xiaodi Yu, Robyn Miller

|Dec 26, 2023
Identification of highly selective SIK1/2 inhibitors that modulate innate immune activation and suppress intestinal inflammation.

Holger Babbe, Thomas B Sundberg, Mark Tichenor

|Jul 21, 2022
Discovery of Potent and Orally Bioavailable Pyridine N-Oxide-Based Factor XIa Inhibitors through Exploiting Nonclassical Interactions.

Guozhang Xu, Zhijie Liu, Xinkang Wang

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Frequent Collaborators

1 joint publications

Zhijie Liu

1 joint publications

Renee L DesJarlais

1 joint publications

Mark J Macielag

1 joint publications

Xiaodi Yu

1 joint publications

Sandeep Somani

1 joint publications

Harrie J M Gijsen

1 joint publications

Jonathan M Blevitt

1 joint publications

Steven D Goldberg

1 joint publications

Katherine Y Blain

1 joint publications

Matthew A Clark

Frequent Collaborators

1 joint publications

Zhijie Liu

1 joint publications

Renee L DesJarlais

1 joint publications

Mark J Macielag

1 joint publications

Xiaodi Yu

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