Brian Ruffell

10PUBLICATIONS
68CO-AUTHORS
Molecular targetsHaematological tumoursCellular immunologyAdversarial machine learningCancer therapy (excl. chemotherapy and radiation therapy)
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Publications (10)

|Sep 11, 2026
KRAS-G12C inhibition-induced enrichment of MHC-Ihigh immune-active tumor cells directs immune-effector TME development to augment therapeutic efficacy.

|Aug 18, 2025
Identification of anti-TIM-3 based checkpoint inhibitor combinations with activity in immunotherapy refractory melanoma models.

Manali S Phadke, Jiannong Li, Sathya Sriramareddy

|Dec 12, 2024
The C5a/C5aR1 Axis Promotes Migration of Tolerogenic Dendritic Cells to Lymph Nodes, Impairing the Anticancer Immune Response.

Yaiza Senent, Ana Remírez, David Repáraz

|Aug 09, 2024
Rapid Autopsy to Define Dendritic Cell Spatial Distribution and T Cell Association in Lung Adenocarcinoma.

Hilal Ozakinci, Xiaofei Song, Gina S Nazario

|Jul 18, 2023
Grading of lung adenocarcinomas with simultaneous segmentation by artificial intelligence (GLASS-AI).

John H Lockhart, Hayley D Ackerman, Kyubum Lee

|Feb 09, 2023
Combination IFNβ and Membrane-Stable CD40L Maximize Tumor Dendritic Cell Activation and Lymph Node Trafficking to Elicit Systemic T-cell Immunity.

Hong Zheng, Xiaoqing Yu, Mohammed L Ibrahim

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Frequent Collaborators

3 joint publications

Theresa A Boyle

2 joint publications

Dana Foresman

2 joint publications

Jonathan V Nguyen

2 joint publications

Carlos MoranSegura