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Orla Cunningham

4PUBLICATIONS

4CO-AUTHORS

Applied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)BiomaterialsBasic pharmacology

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Publications (4)

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|Feb 09, 2021

Combining random mutagenesis, structure-guided design and next-generation sequencing to mitigate polyreactivity of an anti-IL-21R antibody.

Sharon M Campbell, Joseph DeBartolo, James R Apgar

|Jan 18, 2021

Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific antibody for the treatment of solid tumors.

Adam R Root, Gurkan Guntas, Madan Katragadda

|Apr 25, 2020

<i>In vitro</i> affinity optimization of an anti-BDNF monoclonal antibody translates to improved potency in targeting chronic pain states <i>in vivo</i>.

Edwina Stack, Sheridan McMurray, Gordon McMurray

|Dec 23, 2017

Establishing in vitro in vivo correlations to screen monoclonal antibodies for physicochemical properties related to favorable human pharmacokinetics.

Lindsay B Avery, Jason Wade, Mengmeng Wang

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Frequent Collaborators

2 joint publications

Nicole Piche-Nicholas

2 joint publications

James R Apgar

1 joint publications

Lindsay B Avery

1 joint publications

David Cirelli

Frequent Collaborators

2 joint publications

Nicole Piche-Nicholas

2 joint publications

James R Apgar

1 joint publications

Lindsay B Avery

1 joint publications

David Cirelli

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