Karl F Hoffmann

21PUBLICATIONS
79CO-AUTHORS
Medical parasitologyWastewater treatment processesCheminformatics and quantitative structure-activity relationshipsBiologically active moleculesBiomolecular modelling and design
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Publications (21)

|Sep 10, 2026
In vitro sexual dimorphism establishment in schistosomes.

|Apr 10, 2026
Use of a cytochrome P450 humanized mouse model to refine schistosomiasis drug discovery.

Sarah D Davey, Josephine E Forde-Thomas, Benjamin J Hulme

|Dec 10, 2025
Novel 1H-1,2,3-Triazole Derivatives of Praziquantel with TRPMPZQ Modulatory Activity and Antiparasitic Effects on Larvae, Juvenile, and Adult Worms of Schistosoma mansoni.

Floriano Paes Silva Junior, Rafael Ferreira Dantas, Sang-Kyu Park

|Oct 12, 2025
Use of P450 Enzymes for Late-Stage Functionalization in Drug Discovery.

Vincent Poon, Christopher Bailey, Sandra Carvalho

|Dec 04, 2023
Small Molecule Ligands of the BET-like Bromodomain, SmBRD3, Affect Schistosoma mansoni Survival, Oviposition, and Development.

Matthias Schiedel, Darius J B McArdle, Gilda Padalino

|Jul 31, 2023
Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes.

Gilda Padalino, Cassandra A Celatka, Hugh Y Rienhoff

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Frequent Collaborators

4 joint publications

Iain W Chalmers

4 joint publications

Gilda Padalino

3 joint publications

Benjamin J Hulme

3 joint publications

Andrew S MacDonald