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Karl F Hoffmann

20PUBLICATIONS

79CO-AUTHORS

Wastewater treatment processesCheminformatics and quantitative structure-activity relationshipsBiologically active moleculesBiomolecular modelling and designBiomaterials

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Publications (20)

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|Apr 10, 2026

Use of a cytochrome P450 humanized mouse model to refine schistosomiasis drug discovery.

Sarah D Davey, Josephine E Forde-Thomas, Benjamin J Hulme

|Dec 10, 2025

Novel 1<i>H</i>-1,2,3-Triazole Derivatives of Praziquantel with TRPM<sub>PZQ</sub> Modulatory Activity and Antiparasitic Effects on Larvae, Juvenile, and Adult Worms of <i>Schistosoma mansoni</i>.

Floriano Paes Silva Junior, Rafael Ferreira Dantas, Sang-Kyu Park

|Oct 12, 2025

Use of P450 Enzymes for Late-Stage Functionalization in Drug Discovery.

Vincent Poon, Christopher Bailey, Sandra Carvalho

|Dec 04, 2023

Small Molecule Ligands of the BET-like Bromodomain, <i>Sm</i>BRD3, Affect <i>Schistosoma mansoni</i> Survival, Oviposition, and Development.

Matthias Schiedel, Darius J B McArdle, Gilda Padalino

|Jul 31, 2023

Chemical modulation of <i>Schistosoma mansoni</i> lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes.

Gilda Padalino, Cassandra A Celatka, Hugh Y Rienhoff

|Apr 21, 2023

Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022.

Nicola Caldwell, Rana Afshar, Beatriz Baragaña

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Frequent Collaborators

4 joint publications

Iain W Chalmers

4 joint publications

Gilda Padalino

3 joint publications

Andrew S MacDonald

3 joint publications

Ian H Gilbert

2 joint publications

Cornelis H Hokke

2 joint publications

Hermelijn H Smits

2 joint publications

Avril Coghlan

2 joint publications

Helen Whiteland

2 joint publications

Marije E Kuipers

2 joint publications

Dylan W Phillips

Frequent Collaborators

4 joint publications

Iain W Chalmers

4 joint publications

Gilda Padalino

3 joint publications

Andrew S MacDonald

3 joint publications

Ian H Gilbert

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