Charlotte K Brierley

8PUBLICATIONS
59CO-AUTHORS
Molecular targetsHaematological tumoursCancer diagnosisRespiratory diseasesTransplantation immunology
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Publications (8)

|Jul 01, 2026
CAR T cell therapy selectively depletes disease-driving mutant calreticulin cells in xenotransplants and human organoid models of myelofibrosis.

|Jun 09, 2025
Chromothripsis-associated chromosome 21 amplification orchestrates transformation to blast-phase MPN through targetable overexpression of DYRK1A.

Charlotte K Brierley, Bon Ham Yip, Giulia Orlando

|Oct 09, 2024
A proinflammatory stem cell niche drives myelofibrosis through a targetable galectin-1 axis.

Rong Li, Michela Colombo, Guanlin Wang

|Dec 18, 2023
Chromothripsis orchestrates leukemic transformation in blast phase MPN through targetable amplification of DYRK1A.

C K Brierley, B H Yip, G Orlando

|Jun 23, 2022
A tale of two alleles: TP53 and transformation in MPNs.

Charlotte Brierley, Bethan Psaila

|Aug 09, 2020
Low participation rates and disparities in participation in interventional clinical trials for myelodysplastic syndromes.

Charlotte K Brierley, Emily C Zabor, Rami S Komrokji

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Frequent Collaborators

4 joint publications

Bethan Psaila

3 joint publications

Aude-Anais Olijnik

3 joint publications

Adam J Mead

3 joint publications

Antonio Rodriguez-Romera