Paul D Brear

19PUBLICATIONS

85CO-AUTHORS

Molecular targetsBiologically active moleculesGlycoconjugatesMedical biochemistry - proteins and peptides (incl. medical proteomics)Applied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)

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Publications (19)

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|May 14, 2026

Targeting a Pleckstrin Homology Domain with a Lysine-Reactive Covalent Binder.

|May 13, 2026

Towards the targeted protein degradation of CK2: design and synthesis of CAM4066-based PROTACs.

|Mar 24, 2026

Yeast Display Technology Enables Rapid Discovery of Low-Nanomolar Macrocyclic Peptide Inhibitors of Human Angiotensin-Converting Enzyme 2.

Zhanna Romanyuk, Giacomo Bettin, Paul Brear

|Feb 13, 2026

Utilizing Constrained Bicyclic Peptides for <i>In Vitro</i> Diagnostics.

André Shamsabadi, Adam Creamer, Christy J Sadler

|Oct 14, 2025

Exploiting the Cryptic αD Pocket of Casein Kinase 2α (CK2α) to Deliver Highly Potent and Selective Type 1 Inhibitors.

Paul A Glossop, Paul Brear, Susanne Wright

|Mar 08, 2025

Pseudomonas aeruginosa acyl-CoA dehydrogenases and structure-guided inversion of their substrate specificity.

Meng Wang, Prasanthi Medarametla, Thales Kronenberger

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Frequent Collaborators

15 joint publications

Marko Hyvönen

David R Spring

Jessica Iegre

Florian Hollfelder

Michael J Skynner

Daniel H O'Donovan

Maximilian A J Harman

2 joint publications

Liuhong Chen

2 joint publications

Martin Welch

2 joint publications

Eleanor L Atkinson

Frequent Collaborators

15 joint publications

Marko Hyvönen

5 joint publications

David R Spring

4 joint publications

Jessica Iegre

3 joint publications

Florian Hollfelder