Kathleen M McAndrews

20PUBLICATIONS
88CO-AUTHORS
Molecular targetsPredictive and prognostic markersApplied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)Cancer diagnosisNanoscale characterisation
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Publications (20)

|Jul 15, 2026
Oncogenic KRAS Promotes Extracellular DNA Clearance to Drive Immunosuppression in Colorectal Cancer.

|Jul 11, 2026
CDK8 remodels the tumor microenvironment and promotes resistance to KRASG12D inhibitors and daraxonrasib in PDAC.

|Sep 30, 2025
Engineered exosomes with KrasG12D specific siRNA in pancreatic cancer: a phase I study with immunological correlates.

Valerie S Kalluri, Brandon G Smaglo, Krishnan K Mahadevan

|Sep 03, 2025
An allele-agnostic mutant-KRAS inhibitor suppresses tumor maintenance signals and reprograms tumor immunity in pancreatic cancer.

Kathleen M McAndrews, Francesca Paradiso, Clint A Stalnecker

|Aug 12, 2025
CDK8 remodels the tumor microenvironment to resist the therapeutic efficacy of targeted KRAS G12D inhibition in pancreatic ductal adenocarcinoma.

Kathleen M McAndrews, Krishnan K Mahadevan, Bingrui Li

|Mar 17, 2025
KRAS G12D -Specific Targeting with Engineered Exosomes Reprograms the Immune Microenvironment to Enable Efficacy of Immune Checkpoint Therapy in PDAC Patients.

Valerie S LeBleu, Brandon G Smaglo, Krishnan K Mahadevan

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Frequent Collaborators

18 joint publications

Raghu Kalluri

4 joint publications

Anirban Maitra

4 joint publications

Yang Chen

4 joint publications

Krishnan K Mahadevan