Lei Shi

41PUBLICATIONS
109CO-AUTHORS
PharmacogenomicsBiologically active moleculesCheminformatics and quantitative structure-activity relationshipsProteins and peptidesStructural biology (incl. macromolecular modelling)
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Publications (41)

|Oct 22, 2026
Multiple allosteric sites allow for synergistic enhancement of GPCR signaling.

|Sep 10, 2026
A Series of Aryl-Substituted-(biphenyl)methyl-sulfinylmethylthiazoles as Novel and Atypical Dopamine Transporter Inhibitors.

|Jul 05, 2026
Coordinated Subpocket Engagement Underlies Nitazene Potency at the μ-Opioid Receptor.

|Jun 24, 2026
Small-molecule modulation of β-arrestins.

|Jun 22, 2026
Transformer-based framework uncovers state-dependent modular organization and conformational landscapes of the β-arrestin 1 C-terminal tail.

|Apr 01, 2026
A µ-opioid receptor superagonist analgesic with minimal adverse effects.

Juan L Gomez, Emilya N Ventriglia, Zachary J Frangos

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Frequent Collaborators

8 joint publications

Amy Hauck Newman

6 joint publications

J Robert Lane

5 joint publications

R Benjamin Free

5 joint publications

David R Sibley