Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Timothy B Lowinger

6PUBLICATIONS

66CO-AUTHORS

Medical molecular engineering of nucleic acids and proteinsBiologically active moleculesAllergyCharacterisation of biological macromoleculesPharmaceutical delivery technologies

Featured researcher

Get your video featured.

Publish with JoVE

Featured researcher

Get your video featured.

Publish with JoVE

Publications (6)

Sort by Publication Date:

|Jul 31, 2025

PBPK Modeling to Predict Clinical Drug-Drug Interaction and Impact of Hepatic Impairment for an ADC With the Payload Auristatin F-Hydroxypropylamide.

Niyanta Kumar, Vaishali Dixit, Howard Burt

|Mar 03, 2025

XMT-2056, a HER2-Directed STING Agonist Antibody-Drug Conjugate, Induces Innate Antitumor Immune Responses by Acting on Cancer Cells and Tumor-Resident Immune Cells.

Raghida A Bukhalid, Jeremy R Duvall, Kelly Lancaster

|Jul 11, 2024

Tumor cell-directed STING agonist antibody-drug conjugates induce type III interferons and anti-tumor innate immune responses.

Naniye Malli Cetinbas, Travis Monnell, Jahna Soomer-James

|Feb 14, 2024

Development of a Novel DNA Mono-alkylator Platform for Antibody-Drug Conjugates.

Joshua D Thomas, Aleksandr V Yurkovetskiy, Mao Yin

|Sep 29, 2023

Site-Specific Dolasynthen Antibody-Drug Conjugates Exhibit Consistent Pharmacokinetic Profiles across a Wide Range of Drug-to-Antibody Ratios.

Susan M Clardy, Alex Uttard, Bingfan Du

|Jun 09, 2023

Discovery and Preclinical Characterization of XMT-1660, an Optimized B7-H4-Targeted Antibody-Drug Conjugate for the Treatment of Cancer.

Dorin Toader, Shawn P Fessler, Scott D Collins

Pageof 1

Frequent Collaborators

5 joint publications

Dorin Toader

5 joint publications

Kalli C Catcott

5 joint publications

Marc Damelin

4 joint publications

Ling Xu

3 joint publications

Scott D Collins

3 joint publications

Caitlin Routhier

3 joint publications

Elizabeth Ditty

3 joint publications

Pamela Shaw

3 joint publications

Liuliang Qin

3 joint publications

Naniye Malli Cetinbas

Frequent Collaborators

5 joint publications

Dorin Toader

5 joint publications

Kalli C Catcott

5 joint publications

Marc Damelin

4 joint publications

Ling Xu

Top Related Videos

An All-Human Hepatic Culture System for Drug Development Applications

An All-Human Hepatic Culture System for Drug Development Applications

Published on : Oct 20, 2023

Quantifying Antibody-Dependent Cellular Cytotoxicity in a Tumor Spheroid Model: Application for Drug Discovery

Quantifying Antibody-Dependent Cellular Cytotoxicity in a Tumor Spheroid Model: Application for Drug Discovery

Published on : Apr 26, 2024

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo

Published on : Jan 07, 2019

See more related videos

Top Related Videos

An All-Human Hepatic Culture System for Drug Development Applications

An All-Human Hepatic Culture System for Drug Development Applications

Published on : Oct 20, 2023

Quantifying Antibody-Dependent Cellular Cytotoxicity in a Tumor Spheroid Model: Application for Drug Discovery

Quantifying Antibody-Dependent Cellular Cytotoxicity in a Tumor Spheroid Model: Application for Drug Discovery

Published on : Apr 26, 2024

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo

Published on : Jan 07, 2019

See more related videos