Shaojie Wang

7PUBLICATIONS
5CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsBiomolecular modelling and designProteins and peptidesPharmaceutical delivery technologiesReaction engineering (excl. nuclear reactions)
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (7)

|Aug 11, 2025
Design, Synthesis, and Biological Evaluation of Heterocycle-Fused Celastrol Derivatives as Potent Antiosteoporosis Agents by Blocking RANKL-Induced Activation of the NF-κB and MAPK Signaling Pathways.

Xuefeng Fu, Chengjun Wu, Wen Jiang

|Aug 06, 2025
Discovery of 1-Difluoromethyl-3-(3-cyanophenyl)-6-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrazin-8-(7H)-one as a Potent P2Y1 Antagonist for the Treatment of Ischemic Stroke and Myocardial Infarction.

Bing Zhang, Jinxin Li, Ruyu Wang

|May 15, 2025
Design, Synthesis, and Biological Evaluation of 4-(Difluoromethyl)-1H-imidazole-5-carboxylic Acids/4-(3-Cyanophenoxy)pyrimidine-5-carboxylic Acids as P2Y1 Receptor Antagonists for Ischemic Stroke Treatment.

Bing Zhang, Jinxin Li, Qi Li

|Aug 06, 2024
Scaffold Hopping of Pristimerin Provides Derivatives Containing a Privileged Quinoxaline Substructure as Potent Autophagy Inducers in Breast Cancer Cells.

Xuefeng Fu, Yang Jiao, Yao Feng

|Mar 11, 2022
Discovery of a Colon-Targeted Azo Prodrug of Tofacitinib through the Establishment of Colon-Specific Delivery Systems Constructed by 5-ASA-PABA-MAC and 5-ASA-PABA-Diamine for the Treatment of Ulcerative Colitis.

Jiaxing Zhao, Bing Zhang, Qing Mao

|Mar 08, 2022
Thiazolidinedione-Based Structure Modification of Celastrol Provides Thiazolidinedione-Conjugated Derivatives as Potent Agents against Non-Small-Cell Lung Cancer Cells through a Mitochondria-Mediated Apoptotic Pathway.

Xuefeng Fu, Qing Mao, Bing Zhang

Pageof 2

Frequent Collaborators

5 joint publications

Bing Zhang

1 joint publications

Xiaoyu Zhou

1 joint publications

Zheng Liu

1 joint publications

Libo Zou