Ahmed M El-Saghier

8PUBLICATIONS
14CO-AUTHORS
Haematological tumoursMolecular targetsBiologically active moleculesCheminformatics and quantitative structure-activity relationshipsBiomolecular modelling and design
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Publications (8)

|Jul 03, 2026
Design, synthesis, and anti-fibrotic evaluation of novel sulfonamide-embedded 1,2,4-triazinone derivatives in TGF-β-activated hepatic stellate cells (LX-2).

|May 27, 2026
Novel N-4-(5-Amino-7-substituted-triazolotriazinepiperazin-1-yl) Norfloxacin Analogues Exhibit Potent and Selective Anticancer Activity via Topoisomerase Inhibition, Cell-Cycle Arrest, and Apoptosis in A 431 Skin Carcinoma Cells.

|Jul 29, 2025
Novel Benzenesulfonamide Derivatives of 5'-Aminospirotriazolotriazine Exhibit Anti-Inflammatory Activity by Suppressing Pro-Inflammatory Mediators: In Vitro and In Vivo Evaluation Using a Rat Model of Carrageenan-Induced Paw Edema.

Amany M Hamed, Souhaila S Enaili, Walaa I Mohammed

|Apr 26, 2025
Design, Synthesis, and In Silico Studies of New Norfloxacin Analogues with Broad Spectrum Antibacterial Activity via Topoisomerase II Inhibition.

Ahmed M El-Saghier, Laila Abosella, Abdelfattah Hassan

|Jan 25, 2025
Design, Synthesis, Anticancer Screening, and Mechanistic Study of Spiro-N-(4-sulfamoyl-phenyl)-1,3,4-thiadiazole-2-carboxamide Derivatives.

Ahmed M El-Saghier, Hamada Hashem, Sherif A Maher

|Jun 04, 2024
Synthesis, docking and biological evaluation of purine-5-N-isosteresas anti-inflammatory agents.

Ahmed M El-Saghier, Souhaila S Enaili, Aly Abdou

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Frequent Collaborators

3 joint publications

Asmaa M Kadry

3 joint publications

Souhaila S Enaili

3 joint publications

Stefan Bräse

2 joint publications

Aly Abdou