Irina Sevrioukova

18PUBLICATIONS
16CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsMetal cluster chemistryPharmacogenomicsToxicology (incl. clinical toxicology)Biomolecular modelling and design
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (18)

|Jan 10, 2025
Evaluation of Larger Side-Group Functionalities and the Side/End-Group Interplay in Ritonavir-Like Inhibitors of CYP3A4.

Eric R Samuels, Irina F Sevrioukova

|Sep 16, 2024
Mixed Ru(II)-Ir(III) Complexes as Photoactive Inhibitors of the Major Human Drug Metabolizing Enzyme CYP3A4.

Justin J Ahrens, Madeline Denison, Santana Garcia

|Feb 09, 2023
Dynamic Ir(III) Photosensors for the Major Human Drug-Metabolizing Enzyme Cytochrome P450 3A4.

Madeline Denison, Justin J Ahrens, Marilyn N Dunbar

|Oct 27, 2022
Crystal Structure of CYP3A4 Complexed with Fluorol Identifies the Substrate Access Channel as a High-Affinity Ligand Binding Site.

Irina F Sevrioukova

|Aug 22, 2022
Ir(III)-Based Agents for Monitoring the Cytochrome P450 3A4 Active Site Occupancy.

Madeline Denison, Sean J Steinke, Aliza Majeed

|Jul 09, 2022
Interaction of CYP3A4 with Rationally Designed Ritonavir Analogues: Impact of Steric Constraints Imposed on the Heme-Ligating Group and the End-Pyridine Attachment.

Eric R Samuels, Irina F Sevrioukova

Pageof 3

Frequent Collaborators

4 joint publications

Claudia Turro

4 joint publications

Jeremy J Kodanko

2 joint publications

Thomas L Poulos

1 joint publications

Shu-Hao Liou