Joann B Sweasy

6PUBLICATIONS
12CO-AUTHORS
Molecular targetsPhylogeny and comparative analysisLiquid biopsiesComputational physiologyEpigenetics (incl. genome methylation and epigenomics)
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Publications (6)

|Jun 30, 2026
Biochemical, structural and mutational landscapes of base excision repair enzymes and cancer: from atomic resolution to tumor signatures.

|Jan 12, 2026
The S180R Human Germline Variant of DNA Polymerase β Is a Low Fidelity Enzyme with Reduced Flexibility of the Fingers Domain.

Danielle L Sawyer, Brian E Eckenroth, Cristian Chavira

|Sep 19, 2024
Collapsed State Mediates the Low Fidelity of the DNA Polymerase β I260 Mutant.

Carel Fijen, Cristian Chavira, Khadijeh Alnajjar

|May 23, 2024
Modifying the Basicity of the dNTP Leaving Group Modulates Precatalytic Conformational Changes of DNA Polymerase β.

Khadijeh S Alnajjar, Katarina Wang, Isabel Alvarado-Cruz

|Jun 16, 2022
A Human MSH6 Germline Variant Associated With Systemic Lupus Erythematosus Induces Lupus-like Disease in Mice.

Rithy Meas, Joanne Nititham, Kimberly E Taylor

|Apr 29, 2022
The hematopoietic compartment is sufficient for lupus development resulting from the POLB-Y265C mutation.

Tania Rahim, Madison A Levinson, Kelly E W Carufe

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Frequent Collaborators

2 joint publications

Cristian Chavira

1 joint publications

Madison A Levinson

1 joint publications

Rithy Meas

1 joint publications

Patrick M Gaffney