Hiroyuki Takita

5PUBLICATIONS
11CO-AUTHORS
Predictive and prognostic markersCentral nervous systemHuman biophysicsMolecular medicineCell development, proliferation and death
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Publications (5)

|Jun 02, 2022
Coproporphyrin I as an Endogenous Biomarker to Detect Reduced OATP1B Activity and Shift in Elimination Route in Chronic Kidney Disease.

Hiroyuki Takita, Daniel Scotcher, Xiaoyan Chu

|Jan 14, 2022
In Vitro to In Vivo Extrapolation Linked to Physiologically Based Pharmacokinetic Models for Assessing the Brain Drug Disposition.

Yukiko Murata, Sibylle Neuhoff, Amin Rostami-Hodjegan

|Dec 08, 2020
PBPK Model of Coproporphyrin I: Evaluation of the Impact of SLCO1B1 Genotype, Ethnicity, and Sex on its Inter-Individual Variability.

Hiroyuki Takita, Shelby Barnett, Yueping Zhang

|Oct 13, 2020
Physiologically-Based Pharmacokinetic Modelling of Creatinine-Drug Interactions in the Chronic Kidney Disease Population.

Hiroyuki Takita, Daniel Scotcher, Rajkumar Chinnadurai

|Sep 29, 2020
Application of the Nested Enzyme-Within-Enterocyte (NEWE) Turnover Model for Predicting the Time Course of Pharmacodynamic Effects.

Hiroyuki Takita, Adam S Darwich, Amais Ahmad

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Frequent Collaborators

3 joint publications

Aleksandra Galetin

2 joint publications

Amin Rostami-Hodjegan

2 joint publications

Daniel Scotcher

2 joint publications

Kayode Ogungbenro