Chandra Vargeese

7PUBLICATIONS
4CO-AUTHORS
Powder and particle technologyReaction engineering (excl. nuclear reactions)Cheminformatics and quantitative structure-activity relationshipsMolecular and organic electronicsBiomolecular modelling and design
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Publications (7)

|Jan 14, 2026
RNA editing for the treatment of alpha-1 antitrypsin deficiency.

Prashant Monian, Chikdu Shivalila, Genliang Lu

|Aug 16, 2024
Rational design of base, sugar and backbone modifications improves ADAR-mediated RNA editing.

Genliang Lu, Chikdu Shivalila, Prashant Monian

|Apr 18, 2023
Impact of stereopure chimeric backbone chemistries on the potency and durability of gene silencing by RNA interference.

Wei Liu, Naoki Iwamoto, Subramanian Marappan

|Mar 08, 2022
Endogenous ADAR-mediated RNA editing in non-human primates using stereopure chemically modified oligonucleotides.

Prashant Monian, Chikdu Shivalila, Genliang Lu

|Feb 02, 2022
Impact of guanidine-containing backbone linkages on stereopure antisense oligonucleotides in the CNS.

Pachamuthu Kandasamy, Yuanjing Liu, Vincent Aduda

|Jan 21, 2022
Control of backbone chemistry and chirality boost oligonucleotide splice switching activity.

Pachamuthu Kandasamy, Graham McClorey, Mamoru Shimizu

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