David Santamaría

5PUBLICATIONS
70CO-AUTHORS
Molecular targets
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Publications (5)

|Jun 22, 2026
EML4-ALK mediates resistance to KRAS G12C inhibition and induces an oncogenic dependency by rewiring signaling through the wild-type RAS pathway.

|May 27, 2026
Targeted KRASG12V Degradation In Vivo Elicits Lung Adenocarcinoma Regression with Subsequent Relapse from Dysregulated Proteolysis.

|Jul 04, 2025
Cx43 enhances response to BRAF/MEK inhibitors by reducing DNA repair capacity.

Adrián Varela-Vázquez, Amanda Guitián-Caamaño, Paula Carpintero-Fernández

|Aug 30, 2024
RAS-ON inhibition overcomes clinical resistance to KRAS G12C-OFF covalent blockade.

Marie-Julie Nokin, Alessia Mira, Enrico Patrucco

|Sep 11, 2020
Tumor regression and resistance mechanisms upon CDK4 and RAF1 inactivation in KRAS/P53 mutant lung adenocarcinomas.

Laura Esteban-Burgos, Haiyun Wang, Patricia Nieto

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Frequent Collaborators

3 joint publications

Chiara Ambrogio

2 joint publications

Enrico Patrucco

2 joint publications

Alberto Villanueva

2 joint publications

Ernest Nadal