Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Chun-Long Chen

19PUBLICATIONS
81CO-AUTHORS
Radiation therapyGenome structure and regulationHaematological tumoursDeep learningCancer therapy (excl. chemotherapy and radiation therapy)
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (19)

Sort by Publication Date:
|Apr 21, 2026
ATR and TopBP1 oppose to control dormant origin activity and global replication dynamics, providing a first defense against replication stress.

|Dec 02, 2025
Regulated TRESLIN-MTBP loading governs initiation zones and replication timing in human DNA replication.

Xiaoxuan Zhu, Atabek Bektash, Yuki Hatoyama

|Aug 14, 2025
m6A modification in R-loop homeostasis: a potential target for cancer therapeutics.

Minh-Anh Vu, Manuela Spagnuolo, Chun-Long Chen

|Feb 08, 2025
Unravelling single-cell DNA replication timing dynamics using machine learning reveals heterogeneity in cancer progression.

Joseph M Josephides, Chun-Long Chen

|Dec 01, 2023
DAXX promotes centromeric stability independently of ATRX by preventing the accumulation of R-loop-induced DNA double-stranded breaks.

Lia M Pinto, Alexandros Pailas, Max Bondarchenko

|Apr 06, 2023
Mistimed origin licensing and activation stabilize common fragile sites under tight DNA-replication checkpoint activation.

Olivier Brison, Stefano Gnan, Dana Azar

Pageof 4

Frequent Collaborators

3 joint publications

Sami El-Hilali

3 joint publications

Claude Thermes

3 joint publications

Michelle Debatisse

3 joint publications

Yaqun Liu

3 joint publications

Stefano Gnan

2 joint publications

Yong E Zhang

2 joint publications

Jianmin Wu

2 joint publications

Joseph M Josephides

2 joint publications

Olivier Hyrien

2 joint publications

Philippe Pasero

Frequent Collaborators

3 joint publications

Sami El-Hilali

3 joint publications

Claude Thermes

3 joint publications

Michelle Debatisse

3 joint publications

Yaqun Liu

Top Related Videos

Strand-Specific Analysis of Proteins at Replicating DNA Strands by Enrichment and Sequencing of Protein-Associated Nascent DNA Method
08:53

Strand-Specific Analysis of Proteins at Replicating DNA Strands by Enrichment and Sequencing of Protein-Associated Nascent DNA Method

Published on : May 02, 2025

1.1K
Utilizing <sup>18</sup>F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer
06:51

Utilizing <sup>18</sup>F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

Published on : Jul 21, 2018

18.1K
See more related videos

Top Related Videos

Strand-Specific Analysis of Proteins at Replicating DNA Strands by Enrichment and Sequencing of Protein-Associated Nascent DNA Method
08:53

Strand-Specific Analysis of Proteins at Replicating DNA Strands by Enrichment and Sequencing of Protein-Associated Nascent DNA Method

Published on : May 02, 2025

1.1K
Utilizing <sup>18</sup>F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer
06:51

Utilizing <sup>18</sup>F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

Published on : Jul 21, 2018

18.1K
See more related videos