Madelaine P Thorpe

6PUBLICATIONS
7CO-AUTHORS
Biologically active moleculesProteins and peptidesCheminformatics and quantitative structure-activity relationshipsBiomolecular modelling and designWastewater treatment processes
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Publications (6)

|Apr 16, 2025
End-to-End Backbone Cyclization Enhances Passive Permeability of bRo5 Oligomeric Depsipeptides with Nonlinear Size Dependence.

Madelaine P Thorpe, Corey R Hopkins, Jeffrey N Johnston

|Aug 30, 2024
The backbone constitution drives passive permeability independent of side chains in depsipeptide and peptide macrocycles inspired by ent-verticilide.

Madelaine P Thorpe, Abigail N Smith, Daniel J Blackwell

|Jul 03, 2024
Backbone-Determined Antiarrhythmic Structure-Activity Relationships for a Mirror Image, Oligomeric Depsipeptide Natural Product.

Madelaine P Thorpe, Daniel J Blackwell, Bjorn C Knollmann

|Jan 22, 2024
ent-Verticilide B1 Inhibits Type 2 Ryanodine Receptor Channels and is Antiarrhythmic in Casq2 -/- Mice.

Aaron Gochman, Tri Q Do, Kyungsoo Kim

|Nov 17, 2022
Structure-Activity Relationships for the N-Me- Versus N-H-Amide Modification to Macrocyclic ent-Verticilide Antiarrhythmics.

Abigail N Smith, Madelaine P Thorpe, Daniel J Blackwell

|Apr 02, 2022
Resolving Bromonitromethane Sourcing by Synthesis: Preparation at the Decagram Scale.

Madelaine P Thorpe, Abigail N Smith, Michael S Crocker

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Frequent Collaborators

6 joint publications

Jeffrey N Johnston

4 joint publications

Abigail N Smith

3 joint publications

Corey R Hopkins

2 joint publications

Bjorn C Knollmann