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Yu Chen

24PUBLICATIONS
39CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsBiological adaptationProteins and peptidesGenome structure and regulationPharmacogenomics
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Journal

Publications (24)

Sort by Publication Date:
|Mar 16, 2026
Structure-Based Design of Reversible, Quinoline-2(1<i>H</i>)‑one Inhibitors of Serine- and Metallo-Carbapenemases.

Lian M C Jacobs, Priyadarshini Jaishankar, Jeffrey Zheng

|Jan 20, 2026
Dynamic signature of activity-stability tradeoff in lactamase evolution.

Ernesto Arcia, Dimitra Keramisanou, Lian M C Jacobs

|Feb 01, 2025
Distal protein-protein interactions contribute to nirmatrelvir resistance.

Eric M Lewandowski, Xiujun Zhang, Haozhou Tan

|Apr 19, 2024
<i>Staphylococcus aureus</i> FtsZ and PBP4 bind to the conformationally dynamic N-terminal domain of GpsB.

Michael D Sacco, Lauren R Hammond, Radwan E Noor

|Jan 22, 2024
Drug Discovery in the Field of β-Lactams: An Academic Perspective.

Lian M C Jacobs, Patrick Consol, Yu Chen

|Mar 15, 2023
Development of the Safe and Broad-Spectrum Aldehyde and Ketoamide Mpro inhibitors Derived from the Constrained α, γ-AA Peptide Scaffold.

Lei Wang, Chunlong Ma, Michael Dominic Sacco

Pageof 4

Frequent Collaborators

5 joint publications

Adam R Renslo

5 joint publications

Jun Wang

3 joint publications

Lindsey N Shaw

3 joint publications

Prahathees J Eswara

2 joint publications

Sophie E Darch

2 joint publications

Jesper J Madsen

2 joint publications

Michael Thomas Marty

2 joint publications

Michael Dominic Sacco

2 joint publications

Eric M Lewandowski

2 joint publications

Lian M C Jacobs

Frequent Collaborators

5 joint publications

Adam R Renslo

5 joint publications

Jun Wang

3 joint publications

Lindsey N Shaw

3 joint publications

Prahathees J Eswara

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