Harri M Itkonen

13PUBLICATIONS
13CO-AUTHORS
Molecular targetsPolymerisation mechanismsCancer therapy (excl. chemotherapy and radiation therapy)Solid tumours
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Publications (13)

|Sep 02, 2026
Castration-resistant prostate cancer cells are addicted to the high activity of cyclin-dependent kinase 2.

|Aug 21, 2026
CDK12/13 Inhibition Induces DNA Hypomethylation and Sensitizes Cancer Cells to Compounds Targeting DNA-PK.

|Mar 28, 2026
Inactivation of CDK12 Enhances Mitochondrial Efficiency to Suppress DNA Damage.

Aishwarya Gondane, Shivani Yalala, Jing Liang

|Apr 04, 2025
Dynamic O-GlcNAcylation and phosphorylation attract and expel proteins from RNA polymerase II to regulate mRNA maturation.

Aishwarya Gondane, Harri M Itkonen

|Oct 03, 2024
Compromised CDK12 activity causes dependency on the high activity of O-GlcNAc transferase.

Satu Pallasaho, Aishwarya Gondane, Julia Kutz

|May 22, 2024
CDK12-inactivation-induced MYC signaling causes dependency on the splicing kinase SRPK1.

Jing Liang, Aishwarya Gondane, Harri M Itkonen

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Frequent Collaborators

3 joint publications

Ian G Mills

3 joint publications

Aishwarya Gondane

3 joint publications

Jing Liang

2 joint publications

Damien Y Duveau