Robert S Jones

7PUBLICATIONS
17CO-AUTHORS
PharmacogenomicsPredictive and prognostic markersCharacterisation of biological macromoleculesEpigenetics (incl. genome methylation and epigenomics)Basic pharmacology
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Publications (7)

|Oct 24, 2024
Establishing a physiologically based pharmacokinetic framework for aldehyde oxidase and dual aldehyde oxidase-CYP substrates.

Nihan Izat, Jayaprakasam Bolleddula, Pasquale Carione

|Sep 26, 2023
Challenges and Opportunities for In Vitro-In Vivo Extrapolation of Aldehyde Oxidase-Mediated Clearance: Toward a Roadmap for Quantitative Translation.

Nihan Izat, Jayaprakasam Bolleddula, Armina Abbasi

|Jul 31, 2023
Analysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug-Drug Interaction Studies.

Mario Mezler, Robert S Jones, Dewakar Sangaraju

|Jul 10, 2023
Dissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of Drugs.

Sandhya Subash, Dilip K Singh, Deepak S Ahire

|May 17, 2023
Comparisons between human and rodent hepatic glutathione S-Transferase activities reveal sex and species differences.

Michael J Doerksen, Denny Seo, Alexander D Smith

|May 31, 2022
Application of empirical scalars to enable early prediction of human hepatic clearance using IVIVE in drug discovery: an evaluation of 173 drugs.

Robert S Jones, Christian Leung, Jae H Chang

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