Ki-Young Lee
11PUBLICATIONS
5CO-AUTHORS
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Publications (11)
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|Mar 06, 2026
Lgmn targets two distinct GPCRs, PAR2 and µ-OR1, and induces cell death in acute lymphoblastic leukemia through an intracellular Ca²⁺ imbalance triggered by ER Ca²⁺ release.Jung Kwon Lee, Karl Riabowol, Ki-Young Lee
|Apr 08, 2025
L-asparaginase is a PAR2 N-terminal protease that unmasks the PAR2 tethered ligand.Jung Kwon Lee, Karl Riabowol, Xidi Wang
|Aug 15, 2024
L-asparaginase induces IP3R-mediated ER Ca2+ release by targeting µ-OR1 and PAR2 and kills acute lymphoblastic leukemia cells.Jung Kwon Lee, Hamza Kamran, Ki-Young Lee
|May 27, 2024
PKA inhibition kills L-asparaginase-resistant leukemic cells from relapsed acute lymphoblastic leukemia patients.Jung Kwon Lee, Xidi Wang, Jinghua Wang
|Aug 24, 2022
Cdk5 regulates IP3R1-mediated Ca2+ dynamics and Ca2+-mediated cell proliferation.Saranya NavaneethaKrishnan, Vincent Law, Jungkwon Lee
|Dec 21, 2021
CDK5RAP2 loss-of-function causes premature cell senescence via the GSK3β/β-catenin-WIP1 pathway.Xidi Wang, Patrick Sipila, Zizhen Si
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