Zhuo Chen

14PUBLICATIONS
5CO-AUTHORS
Preventative health careBiologically active moleculesMolecular targetsRespiratory diseasesBiomolecular modelling and design
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Publications (14)

|May 11, 2026
Identification of an Hsp110/HDAC6 Dual-Target Inhibitor for the Effective Treatment of Pulmonary Arterial Hypertension via Synergistic Blockade of Vascular Remodeling.

|Apr 22, 2026
Identification of Nitric Oxide-Donating Lenumlostat Derivatives with Dual Activities of Extracellular Matrix Dysregulation Inhibition and Pulmonary Vasodilation for the Treatment of Pulmonary Arterial Hypertension.

|Dec 19, 2025
Pan-Cdk inhibitor ZK304709 suppresses Cdc20 expression and potentiates the anticancer activity of apcin in HeLa cervical cancer cells.

Xiangyang Le, Qingsong Chen, Shuyang Cao

|Dec 13, 2025
Design and Optimization of LOXL2 and sGC Dual-Target Regulators Targeting Extracellular Matrix Dysregulation and Vasodilation for the Treatment of Pulmonary Arterial Hypertension.

Yuanbo Hu, Yu Wang, Wenhua Tan

|Oct 17, 2025
Discovery of Cdc20/Hsp90 Dual-Target Inhibitors with Potent Antitumor Activity for Therapy of Acquired Resistant Melanoma.

Qingsong Chen, Xiangyang Le, Qiwan Wen

|Mar 05, 2025
Discovery of a novel 2,4-thiazolidinedione derivative as dual inhibitor of β-catenin/TCF4 interaction and tubulin polymerization in colon cancer cells.

Yating Guo, Meng Cao, Zhaohui Li

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Frequent Collaborators

10 joint publications

Qianbin Li

2 joint publications

Xiangyang Le

1 joint publications

Liqing Hu

1 joint publications

Qingsong Chen