Christopher M Dobson

25PUBLICATIONS
72CO-AUTHORS
Metabolic medicineNeurology and neuromuscular diseasesCharacterisation of biological macromoleculesMolecular targetsMedical infection agents (incl. prions)
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Publications (25)

|Jul 08, 2021
Two human metabolites rescue a C. elegans model of Alzheimer's disease via a cytosolic unfolded protein response.

Priyanka Joshi, Michele Perni, Ryan Limbocker

|Mar 23, 2021
The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells.

Roberta Cascella, Serene W Chen, Alessandra Bigi

|Nov 05, 2020
Small-molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer's disease.

Gabriella T Heller, Francesco A Aprile, Thomas C T Michaels

|Sep 29, 2020
Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies.

Sara Linse, Tom Scheidt, Katja Bernfur

|Aug 15, 2020
Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism.

Ryan Limbocker, Benedetta Mannini, Francesco S Ruggeri

|Aug 12, 2020
Direct measurement of lipid membrane disruption connects kinetics and toxicity of Aβ42 aggregation.

Patrick Flagmeier, Suman De, Thomas C T Michaels

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