Aleem Gangjee

7PUBLICATIONS
19CO-AUTHORS
Cancer geneticsCheminformatics and quantitative structure-activity relationshipsPharmacogenomicsBiologically active molecules
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Publications (7)

|Feb 20, 2024
Mitochondrial and Cytosolic One-Carbon Metabolism Is a Targetable Metabolic Vulnerability in Cisplatin-Resistant Ovarian Cancer.

Adrianne Wallace-Povirk, Carrie O'Connor, Aamod S Dekhne

|Feb 07, 2024
Structural Characterization of 5-Substituted Pyrrolo[3,2-d]pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2.

Jade M Katinas, Md Junayed Nayeen, Mathew Schneider

|Dec 20, 2023
Discovery of Tumor-Targeted 6-Methyl Substituted Pemetrexed and Related Antifolates with Selective Loss of RFC Transport.

Krishna Kaku, Manasa P Ravindra, Nian Tong

|Aug 15, 2023
Structure-Based Design of Transport-Specific Multitargeted One-Carbon Metabolism Inhibitors in Cytosol and Mitochondria.

Md Junayed Nayeen, Jade M Katinas, Tejashree Magdum

|May 18, 2023
Multitargeted 6-Substituted Thieno[2,3-d]pyrimidines as Folate Receptor-Selective Anticancer Agents that Inhibit Cytosolic and Mitochondrial One-Carbon Metabolism.

Nian Tong, Jennifer Wong-Roushar, Adrianne Wallace-Povirk

|Apr 28, 2018
Fluorine-Substituted Pyrrolo[2,3- d]Pyrimidine Analogues with Tumor Targeting via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis.

Manasa Ravindra, Mike R Wilson, Nian Tong

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Frequent Collaborators

4 joint publications

Zhanjun Hou

4 joint publications

Larry H Matherly

2 joint publications

Adrianne Wallace-Povirk

2 joint publications

Charles E Dann