Philippe Roche

14PUBLICATIONS
41CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsCharacterisation of biological macromoleculesCardiology (incl. cardiovascular diseases)Molecular targetsBiologically active molecules
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Publications (14)

|Jan 07, 2026
Engineering SIRPα conformational plasticity to reveal a cryptic pocket suitable for structure-based drug design.

M Storder, S Barelier, F Cordier

|Aug 15, 2025
NanoDSF Screening for Anti-tubulin Agents Uncovers New Structure-Activity Insights.

Viktoriia Baksheeva, Romain La Rocca, Diane Allegro

|Apr 30, 2024
ChemoDOTS: a web server to design chemistry-driven focused libraries.

Laurent Hoffer, Guillaume Charifi-Hoareau, Sarah Barelier

|Aug 21, 2023
Cinacalcet Reverses Short QT Interval in Familial Hypocalciuric Hypercalcemia Type 1.

Thomas Cuny, Pauline Romanet, Michelle Goldsworthy

|May 29, 2023
From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia.

Magali Saez-Ayala, Laurent Hoffer, Sébastien Abel

|Mar 20, 2023
Discovery of a PDZ Domain Inhibitor Targeting the Syndecan/Syntenin Protein-Protein Interaction: A Semi-Automated "Hit Identification-to-Optimization" Approach.

Laurent Hoffer, Manon Garcia, Raphael Leblanc

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Frequent Collaborators

10 joint publications

Xavier Morelli

7 joint publications

Stéphane Betzi

2 joint publications

Sarah Barelier

2 joint publications

Karine Barral