Brittany N Flores

2PUBLICATIONS
19CO-AUTHORS
Molecular targetsNeural engineering
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Publications (2)

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|Aug 18, 2025
Investigational eIF2B activator DNL343 modulates the integrated stress response in preclinical models of TDP-43 pathology and individuals with ALS in a randomized clinical trial.

Brittany N Flores, Seungyoon B Yu, Isaac V Cohen

|Mar 21, 2024
Discovery of DNL343: A Potent, Selective, and Brain-Penetrant eIF2B Activator Designed for the Treatment of Neurodegenerative Diseases.

Robert A Craig, Javier De Vicente, Anthony A Estrada

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Frequent Collaborators

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Javier De Vicente

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Jianwen A Feng

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Ernie Yulyaningsih

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Maksim Osipov

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Seungyoon B Yu

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Isaac V Cohen

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Maurits Vissers

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Meredith E K Calvert

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Jules A A C Heuberger

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Katie Saund

Frequent Collaborators

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Javier De Vicente

1 joint publications

Jianwen A Feng

1 joint publications

Ernie Yulyaningsih

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Maksim Osipov

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