María Dolores Ledesma

8PUBLICATIONS
28CO-AUTHORS
NeonatologyCellular nervous systemMedical biochemistry - amino acids and metabolitesMetabolic medicineMolecular medicine
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Publications (8)

|Aug 12, 2026
Targeting CD44 reverses sphingomyelin-induced oligodendrocyte maturation arrest in acid sphingomyelinase deficiency.

|Oct 23, 2024
Enhanced mGluR5 intracellular activity causes psychiatric alterations in Niemann Pick type C disease.

Ana Toledano-Zaragoza, Violeta Enriquez-Zarralanga, Sara Naya-Forcano

|Apr 06, 2023
Sphingomyelin 16:0 is a therapeutic target for neuronal death in acid sphingomyelinase deficiency.

Ángel Gaudioso, Xuntian Jiang, Josefina Casas

|Sep 29, 2021
Neutral sphingomyelinase mediates the co-morbidity trias of alcohol abuse, major depression and bone defects.

Liubov S Kalinichenko, Christiane Mühle, Tianye Jia

|Oct 05, 2020
Inhibition of fatty acid amide hydrolase prevents pathology in neurovisceral acid sphingomyelinase deficiency by rescuing defective endocannabinoid signaling.

Adrián Bartoll, Ana Toledano-Zaragoza, Josefina Casas

|Sep 20, 2019
NPC1 enables cholesterol mobilization during long-term potentiation that can be restored in Niemann-Pick disease type C by CYP46A1 activation.

Daniel N Mitroi, Guadalupe Pereyra-Gómez, Beatriz Soto-Huelin

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Frequent Collaborators

1 joint publications

Héctor Peinado

1 joint publications

Lluis Samaranch

1 joint publications

Azucena Pérez-Cañamás

1 joint publications

Beatriz Soto-Huelin