Julie Secombe

11PUBLICATIONS
8CO-AUTHORS
Epigenetics (incl. genome methylation and epigenomics)Neurology and neuromuscular diseasesDevelopmental genetics (incl. sex determination)Child and adolescent developmentEvolution of developmental systems
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (11)

|Aug 06, 2026
A KDM5 variant outside the catalytic Jumonji C domain disrupts demethylase activity and alters the proximity interactome.

|Jan 15, 2026
Individuals with reported and novel KDM5C variants present with seizures, a feature recapitulated in a Drosophila model.

Bethany K Terry, Amira Mahoney, Brian I Lee

|Sep 26, 2025
Individuals with reported and novel KDM5C variants present with seizures, a feature recapitulated in a Drosophila model.

Bethany K Terry, Amira Mahoney, Brian Lee

|Dec 16, 2024
The histone demethylase KDM5 has insulator activity in the brain.

Matanel Yheskel, Melissa A Castiglione, Richard D Kelly

|Apr 10, 2024
KDM5-mediated transcriptional activation of ribosomal protein genes alters translation efficiency to regulate mitochondrial metabolism in neurons.

Matanel Yheskel, Hayden A M Hatch, Erika Pedrosa

|Oct 06, 2023
KDM5-mediated activation of genes required for mitochondrial biology is necessary for viability in Drosophila.

Michael F Rogers, Owen J Marshall, Julie Secombe

Pageof 2

Frequent Collaborators

3 joint publications

Hayden AM Hatch

2 joint publications

Helen M Belalcazar

2 joint publications

Michael F Rogers

2 joint publications

Bethany K Terry