Hiroaki Kato

5PUBLICATIONS
12CO-AUTHORS
Biomolecular modelling and designPharmacogenomicsCharacterisation of biological macromolecules
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (5)

|May 31, 2022
Structure-based alteration of tryptophan residues of the multidrug transporter CmABCB1 to assess substrate binding using fluorescence spectroscopy.

Yoshiki Inoue, Tomohiro Yamaguchi, Tetsuo Otsuka

|Mar 08, 2021
The crystal structure of the CmABCB1 G132V mutant, which favors the outward-facing state, reveals the mechanism of the pivotal joint between TM1 and TM3.

Keita Matsuoka, Toru Nakatsu, Hiroaki Kato

|Dec 04, 2020
ABCB1/MDR1/P-gp employs an ATP-dependent twist-and-squeeze mechanism to export hydrophobic drugs.

Atsushi Kodan, Ryota Futamata, Yasuhisa Kimura

|Jan 10, 2019
Inward- and outward-facing X-ray crystal structures of homodimeric P-glycoprotein CmABCB1.

Atsushi Kodan, Tomohiro Yamaguchi, Toru Nakatsu

Pageof 1