Lin-Kun An

11PUBLICATIONS
21CO-AUTHORS
Biologically active moleculesMolecular targetsIndustrial microbiology (incl. biofeedstocks)F-block chemistryCheminformatics and quantitative structure-activity relationships
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Journal

Publications (11)

|Jun 26, 2026
Development of APH003─a Highly Potent, Selective, and Orally Bioavailable IRAK4 PROTAC Degrader for the Treatment of Inflammatory Diseases.

|Jul 21, 2025
Synthesis and investigation of thieno[2,3-b]pyridines that restore activity of topotecan.

Emily K Paulin, Natalie A Haverkate, Petr Tomek

|Jun 17, 2025
Discovery of APH02174 as a Highly Selective and Orally Bioavailable IRAK4 Degrader for the Treatment of Inflammatory Diseases.

Xi-Wei Wu, Zhao-Min Chen, Cui Gao

|Apr 29, 2025
Synthesis of 5,9- and 5,8-Diaminoalkoxy Substituted Benzophenanthridinone Analogues as Tyrosyl-DNA Phosphodiesterase 1 Inhibitors and Their Radiosensitizing Activity.

De-Xuan Hu, Chao Qin, Li-Shuang Guo

|Oct 12, 2023
General Synthesis of N-CF3 Heteroaryl Amides via Successive Fluorination and Acylation of Sterically Hindered Isothiocyanates.

Min Tao, Jiasheng Qian, Zuanguang Chen

|Mar 17, 2023
Synthesis and Biological Activities of 11- and 12-Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB and Tyrosyl-DNA Phosphodiesterase 1 Inhibitors.

Hao Yang, Chao Qin, Min Wu

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Frequent Collaborators

2 joint publications

Ding Li

1 joint publications

Xiao-Jiang Hao

1 joint publications

Hai-Yang Liu

1 joint publications

Long-Gao Xiao