Michael W Handlogten

6PUBLICATIONS
7CO-AUTHORS
Bioprocessing, bioproduction and bioproductsSeparation technologiesIndustrial molecular engineering of nucleic acids and proteinsApplied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)
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Publications (6)

|Oct 22, 2024
Elevated endoplasmic reticulum pH is associated with high growth and bisAb aggregation in CHO cells.

Kevin S McFarland, Kaitlin Hegadorn, Michael J Betenbaugh

|Feb 19, 2022
Engineering redox sensors into CHO cells enables near-real-time quantification of intracellular redox in bioprocesses.

Kevin S McFarland, Jie Zhu, Pritam Sinharoy

|Jul 08, 2020
Prevention of Fab-arm exchange and antibody reduction via stabilization of the IgG4 hinge region.

Michael W Handlogten, Li Peng, Elizabeth A Christian

|Jan 21, 2020
Online control of cell culture redox potential prevents antibody interchain disulfide bond reduction.

Michael W Handlogten, Jihong Wang, Sanjeev Ahuja

|Jan 14, 2020
Impact of enzymatic reduction on bivalent bispecific antibody fragmentation and loss of product purity upon reoxidation.

Nicole Swope, Wai Keen Chung, Mingyan Cao

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