Tom Brown

73PUBLICATIONS
153CO-AUTHORS
Medical molecular engineering of nucleic acids and proteinsBiologically active moleculesReaction engineering (excl. nuclear reactions)Epigenetics (incl. genome methylation and epigenomics)Glycoconjugates
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Publications (73)

|Jul 22, 2026
A versatile strategy for oligonucleotide functionalization via on-support phosphitylation.

|Jun 09, 2026
5'-Palmitate Lipid and Internal LNA-Piperidyl Triesters Enhance the RNA Affinity and Activity of Splice-Switching Oligonucleotides.

|May 19, 2026
Non-enzymatic conversion of RNA sequence information into DNA by squaramide ligation for accurate RNA quantification.

|Dec 03, 2025
Molecular basis for CSB stimulation of the SNM1A DNA repair nuclease.

Rebecca Roddan, Matthew A Schaich, William J Nathan

|Nov 24, 2025
Biophysical and biological properties of splice-switching oligonucleotides and click conjugates containing LNA-phosphothiotriester linkages.

Debashis Dhara, Alyssa C Hill, Abinaya Ramesh

|Nov 06, 2025
Enzymatic Synthesis of Modified RNA Containing 5-Methyl- or 5-Ethylpyrimidines or Substituted 7-Deazapurines and Influence of the Modifications on Stability, Translation, and CRISPR-Cas9 Cleavage.

Tania Sanchez-Quirante, Erika Kužmová, Miguel Riopedre-Fernandez

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Frequent Collaborators

37 joint publications

Afaf Helmy El-Sagheer

11 joint publications

Antonios G Kanaras

7 joint publications

Ysobel R Baker

4 joint publications

Sven Epple