Jessica Downs

8PUBLICATIONS
23CO-AUTHORS
Genome structure and regulationMolecular targetsCancer therapy (excl. chemotherapy and radiation therapy)Haematological tumoursCell development, proliferation and death
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Publications (8)

|Jan 15, 2026
Boundary issues: SWI/SNF shapes chromatin patterns in and around centromeres.

Karen A Lane, Alison Harrod, Jessica Downs

|Nov 27, 2025
The CIP2A-TOPBP1 axis facilitates mitotic DNA repair via MiDAS and MMEJ.

Peter R Martin, Jadwiga Nieminuszczy, Zuza Kozik

|Feb 26, 2025
PBRM1 directs PBAF to pericentromeres and protects centromere integrity.

Karen A Lane, Alison Harrod, Lillian Wu

|Jul 28, 2022
PBAF loss leads to DNA damage-induced inflammatory signaling through defective G2/M checkpoint maintenance.

Hugang Feng, Karen A Lane, Theodoros I Roumeliotis

|Apr 02, 2022
Aneuploidy tolerance caused by BRG1 loss allows chromosome gains and recovery of fitness.

Federica Schiavoni, Pedro Zuazua-Villar, Theodoros I Roumeliotis

|Nov 14, 2020
CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks.

Magdalena B Rother, Stefania Pellegrino, Rebecca Smith

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